L-Glutamine is the most abundant amino acid found in the body and the largest concentration of L-Glutamine is found primarily in the lining of the small intestine. The gastrointestinal tract cannot function without glutamine. Integrative physicians use L-Glutamine therapy to normalize and balance the gastro intestinal tract. There is overwhelming scientific proof that L-Glutamine will prevent and reverse “leaky gut syndrome” and all its troublesome consequences, including allergies, food sensitivities, the “leaking out” of pathogens into the bloodstream and in many cases arthritic pain. In fact, when it was first discovered, L-Glutamine was known as “intestinal permeability factor.” It is by far the most important nutrient for intestinal health. The importance of glutamine for the intestines is enormous. L-Glutamine is the chief source of energy for the cells of the intestinal lining. Glutamine also maintains the structural integrity of the intestinal lining, supporting its quick turnover for normalizing gut function. Recent research confirms that L-Glutamine can repair damage to intestinal lining cause by over-the-counter pain relievers. L-Glutamine strengthens the immune system. Glutamine is the primary source of energy for the various cells of the immune system, including T cells and macrophages. Strenuous exercise, viral and bacterial infections, and stress and trauma in general cause glutamine depletion that starves the immune cells. They decline in number and/or show diminished activity. Up to 40 g of glutamine a day can be used to sustain the immune system of AIDS or cancer patients. More typical doses, such as 2-5 g/day, should be sufficient for healthy people. L-Glutamine helps maintain muscle mass, something that becomes increasingly more difficult as we age. Glutamine is one of the favorite supplements of body builders who refer to L-glutamine as muscle food. It has recently been discovered that glutamine is an important source of fuel for the heart muscle. L-Glutamine serves as a substrate for the production of ATP, the body’s energy molecule. This is yet another reason why glutamine is so important during exercise and for increasing endurance.