Magnesium is one of the most versatile nutritive minerals. Magnesium is an essential activator of approximately 300 enzymes in the body. It is also required for proper nerve function, heart rhythm and bone integrity. Magnesium is easily lost from the body because of stress, strenuous exercise, coffee and alcohol. Certain medications can deplete magnesium as well. Studies suggest as much as 75% of the population in Western countries consume less than the RDA for magnesium. Magnesium supplementation may be important for large numbers of people. High Absorption Magnesium contains 100% pure pharmaceutical-grade magnesium glycinate. The glycinate form of magnesium (magnesium bound to the amino acid Glycine) is a highly beneficial amino acid that functions as an “inhibitory neurotransmitter” (calms the nervous system), supports collagen production (connective tissue) and benefits muscle tissue. Glycine is a highly effective mineral chelator, and makes magnesium glycinate the most bio-available form or magnesium. This is because it is a low-molecular-weight amino acid, hence is easily transported across the intestinal membrane. A study conducted at Weber State University found magnesium glycinate was absorbed up to four times more effectively than typical magnesium supplements. Magnesium glycinate does not cause stomach upset or diarrhea, which can accompany the use of magnesium salts used in other magnesium supplements. A small clinical trial was done at the University of Chicago, which tested patients with severe malabsorption problems for magnesium glycinate tolerance. In contrast to other forms of magnesium tested, it showed excellent tolerance. Several university studies on magnesium are currently using magnesium glycinate as the test material.