Extensive research has shown the effectiveness of L-Carnitine in applications such as exercise, heart health, weight management, and brain anti-aging. A major cause of aging is the deterioration of the energy-producing components of the cell which results in reduced cellular metabolic activity, the accumulation of cellular debris, and eventual death of the cell. One of the most effective nutrients to maintain youthful cellular energy metabolism is the amino acid Acetyl-L-Carnitine, which functions to protect cells from the effects of aging. Acetyl L-Carnitine assists in the transport of fat through the cell membrane and into the mitochondria (the power producing unit of the cell) within the cell, where these fats are utilized to produce the cellular energy ATP. In studies from the University of California at Berkeley (Hagen TM et al., 1998) acetyl-L-Carnitine significantly reversed age-associated mitochondrial decay. It increased cellular respiration, & membrane potential. Recent attention has been placed upon its ability to protect and increase receptors in the brain that normally decline with age. As such, Acetyl-L-Carnitine is being used in high doses to treat senile dementias, and has also been shown to help remove lipofuscin, a potassium age buildup, a function that improves brain function. This could help improve short-term memory improves and mental focus. Acetyl-L-Carnitine is responsible for shuttling fats in and out of cells, some indications are that use may benefit those on a diet to help lose weight. Acetyl-L-Carnitine has been shown to improve energy production within brain cells and is considered a neuroprotective agent because of its antioxidant action and membrane stabilizing effects. Several controlled clinical studies in Europe show that acetyl-L-Carnitine slows down the natural course of Alzheimer’s disease in many important respects. (Calvani M et al., 1992).